Exclusive destruction of mitotic spindles in human cancer cells

We identified target proteins modified by phenanthrenes that cause exclusive eradication of human cancer cells. The cytotoxic activity of the phenanthrenes in a variety of human cancer cells is attributed by these findings to post translational modifications of NuMA and kinesins HSET/kifC1 and kif18...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Visochek, Leonid, Castiel, Asher, Mittelman, Leonid, Elkin, Michael, Atias, Dikla, Golan, Talia, Izraeli, Shai, Peretz, Tamar, Cohen-Armon, Malka
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400547/
https://ncbi.nlm.nih.gov/pubmed/28209915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15343
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