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Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEAD
TEAD (TEA/ATTS domain) transcription factors are the most distal effectors of the Hippo pathway. YAP (Yes-associated protein) is a coactivator protein which, upon binding to TEAD proteins, stimulates their transcriptional activity. Since the Hippo pathway is deregulated in various cancers, designing...
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| Publicat a: | eLife |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5400505/ https://ncbi.nlm.nih.gov/pubmed/28430104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25068 |
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