PET Monitoring the Induction of HSF1/HSP70 Expression Following 17-AAG Treatment

RATIONALE: The cell response to proteotoxic cell stresses is mediated primarily through activation of heat shock factor 1 (HSF-1). This transcription factor plays a major role in the regulation of the heat shock proteins (HSPs), including HSP70. We demonstrate that an [124I]iodide-pQHNIG70 PET-repor...

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Detalhes bibliográficos
Publicado no:Mol Imaging
Main Authors: Doubrovin, Mikhail, Che, Jian T., Serganova, Inna, Moroz, Ekaterina, Solit, David B., Ageyeva, Lyudmila, Kochetkova, Tatiana, Pillarsetti, Nagavarakishore, Finn, Ronald, Rosen, Neal, Blasberg, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400108/
https://ncbi.nlm.nih.gov/pubmed/22418029
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