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Maleimide scavenging enhances determination of protein S-palmitoylation state in acyl-exchange methods

S-palmitoylation (S-acylation) is an emerging dynamic post-translational modification of cysteine residues within proteins. Current assays for protein S-palmitoylation involve either in vivo labelling or chemical cleavage of S-palmitoyl groups to reveal a free cysteine sulfhydryl that can be subsequ...

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Bibliografiske detaljer
Udgivet i:Biotechniques
Main Authors: Hurst, Charlotte H., Turnbull, Dionne, Plain, Fiona, Fuller, William, Hemsley, Piers A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400063/
https://ncbi.nlm.nih.gov/pubmed/28193150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2144/000114516
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