Microglial TNFα Induces COX2 and PGI2 Synthase Expression in Spinal Endothelial Cells during Neuropathic Pain

Prostaglandins (PGs) are typical lipid mediators that play a role in homeostasis and disease. They are synthesized from arachidonic acid by cyclooxygenase 1 (COX1) and COX2. Although COX2 has been reported to be upregulated in the spinal cord after nerve injury, its expression and functional roles i...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Kanda, Hirosato, Kobayashi, Kimiko, Yamanaka, Hiroki, Okubo, Masamichi, Noguchi, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399753/
https://ncbi.nlm.nih.gov/pubmed/28451639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0064-17.2017
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