Up-regulation of platelet-activating factor synthases and its receptor in spinal cord contribute to development of neuropathic pain following peripheral nerve injury

BACKGROUND: Platelet-activating factor (PAF; 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a lipid mediator derived from cell membrane. It has been reported that PAF is involved in various pathological conditions, such as spinal cord injury, multiple sclerosis, neuropathic pain and intrathecal ad...

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Detalhes bibliográficos
Main Authors: Okubo, Masamichi, Yamanaka, Hiroki, Kobayashi, Kimiko, Kanda, Hirosato, Dai, Yi, Noguchi, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293010/
https://ncbi.nlm.nih.gov/pubmed/22296727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-8
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