Macrophage-Colony Stimulating Factor Derived from Injured Primary Afferent Induces Proliferation of Spinal Microglia and Neuropathic Pain in Rats

Peripheral nerve injury induces proliferation of microglia in the spinal cord, which can contribute to neuropathic pain conditions. However, candidate molecules for proliferation of spinal microglia after injury in rats remain unclear. We focused on the colony-stimulating factors (CSFs) and interleu...

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Veröffentlicht in:PLoS One
Hauptverfasser: Okubo, Masamichi, Yamanaka, Hiroki, Kobayashi, Kimiko, Dai, Yi, Kanda, Hirosato, Yagi, Hideshi, Noguchi, Koichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829214/
https://ncbi.nlm.nih.gov/pubmed/27071004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153375
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