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Phenobarbital Meets Phosphorylation of Nuclear Receptors
Phenobarbital was the first therapeutic drug to be characterized for its induction of hepatic drug metabolism. Essentially at the same time, cytochrome P450, an enzyme that metabolizes drugs, was discovered. After nearly 50 years of investigation, the molecular target of phenobarbital induction has...
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| Veröffentlicht in: | Drug Metab Dispos |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399647/ https://ncbi.nlm.nih.gov/pubmed/28356313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.074872 |
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