טוען...
Effect of Disease-Related Changes in Plasma Albumin on the Pharmacokinetics of Naproxen in Male and Female Arthritic Rats
Naproxen (NPX) is used in the treatment of rheumatoid arthritis (RA) for alleviation of pain and inflammation. In view of the extensive albumin binding of NPX, this study investigates whether chronic inflammation and sex influence the physiologic albumin concentrations, plasma protein binding, and p...
שמור ב:
הוצא לאור ב: | Drug Metab Dispos |
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Main Authors: | , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399645/ https://ncbi.nlm.nih.gov/pubmed/28246126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.074500 |
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