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Suppression of lung adenocarcinoma through menin and polycomb gene-mediated repression of growth factor pleiotrophin
Menin up-regulates transcription of cell cycle inhibitors to suppress endocrine tumors, but it is poorly understood how menin suppresses non-endocrine tumors such as lung cancer. Here, we show that menin inhibits proliferation of human lung cancer cells and growth of lung cancer in mice. The menin-m...
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| Vydáno v: | Oncogene |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399538/ https://ncbi.nlm.nih.gov/pubmed/19749796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.273 |
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