Tumor Suppressor Menin Represses Paired Box Gene 2 Expression via Wilms Tumor Suppressor Protein-Polycomb Group Complex

Tumor suppressor menin, the product of the MEN1 gene, plays a key role in controlling histone 3 lysine 4 trimethylation (H3K4me3) and gene transcription, which can regulate proliferation, apoptosis, and differentiation. However, little is known as to whether menin controls gene expression and cell p...

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Bibliographic Details
Main Authors: Xu, Bin, Zeng, De-quan, Wu, Yuan, Zheng, Rong, Gu, Le, Lin, Xiao, Hua, Xianxin, Jin, Guang-Hui
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077594/
https://ncbi.nlm.nih.gov/pubmed/21378168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.197830
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