RUNX1/ETO blocks selectin-mediated adhesion via epigenetic silencing of PSGL-1

RUNX1/ETO (RE), the t(8;21)-derived leukemic transcription factor associated with acute myeloid leukemia (AML) development, deregulates genes involved in differentiation, self-renewal and proliferation. In addition, these cells show differences in cellular adhesion behavior whose molecular basis is...

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Publicat a:Oncogenesis
Autors principals: Ponnusamy, K, Kohrs, N, Ptasinska, A, Assi, S A, Herold, T, Hiddemann, W, Lausen, J, Bonifer, C, Henschler, R, Wichmann, C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399174/
https://ncbi.nlm.nih.gov/pubmed/25867177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2015.6
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