MiR144/451 Expression Is Repressed by RUNX1 During Megakaryopoiesis and Disturbed by RUNX1/ETO

A network of lineage-specific transcription factors and microRNAs tightly regulates differentiation of hematopoietic stem cells along the distinct lineages. Deregulation of this regulatory network contributes to impaired lineage fidelity and leukemogenesis. We found that the hematopoietic master reg...

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Publicado en:PLoS Genet
Main Authors: Kohrs, Nicole, Kolodziej, Stephan, Kuvardina, Olga N., Herglotz, Julia, Yillah, Jasmin, Herkt, Stefanie, Piechatzek, Alexander, Salinas Riester, Gabriela, Lingner, Thomas, Wichmann, Christian, Bonig, Halvard, Seifried, Erhard, Platzbecker, Uwe, Medyouf, Hind, Grez, Manuel, Lausen, Jörn
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798443/
https://ncbi.nlm.nih.gov/pubmed/26990877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005946
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