MiR144/451 Expression Is Repressed by RUNX1 During Megakaryopoiesis and Disturbed by RUNX1/ETO

A network of lineage-specific transcription factors and microRNAs tightly regulates differentiation of hematopoietic stem cells along the distinct lineages. Deregulation of this regulatory network contributes to impaired lineage fidelity and leukemogenesis. We found that the hematopoietic master reg...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Kohrs, Nicole, Kolodziej, Stephan, Kuvardina, Olga N., Herglotz, Julia, Yillah, Jasmin, Herkt, Stefanie, Piechatzek, Alexander, Salinas Riester, Gabriela, Lingner, Thomas, Wichmann, Christian, Bonig, Halvard, Seifried, Erhard, Platzbecker, Uwe, Medyouf, Hind, Grez, Manuel, Lausen, Jörn
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798443/
https://ncbi.nlm.nih.gov/pubmed/26990877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005946
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