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MiR144/451 Expression Is Repressed by RUNX1 During Megakaryopoiesis and Disturbed by RUNX1/ETO

A network of lineage-specific transcription factors and microRNAs tightly regulates differentiation of hematopoietic stem cells along the distinct lineages. Deregulation of this regulatory network contributes to impaired lineage fidelity and leukemogenesis. We found that the hematopoietic master reg...

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Publicat a:PLoS Genet
Autors principals: Kohrs, Nicole, Kolodziej, Stephan, Kuvardina, Olga N., Herglotz, Julia, Yillah, Jasmin, Herkt, Stefanie, Piechatzek, Alexander, Salinas Riester, Gabriela, Lingner, Thomas, Wichmann, Christian, Bonig, Halvard, Seifried, Erhard, Platzbecker, Uwe, Medyouf, Hind, Grez, Manuel, Lausen, Jörn
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798443/
https://ncbi.nlm.nih.gov/pubmed/26990877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005946
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