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RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation
The activity of antagonizing transcription factors represents a mechanistic paradigm of bidirectional lineage–fate control during hematopoiesis. At the megakaryocytic/erythroid bifurcation, the crossantagonism of krueppel-like factor 1 (KLF1) and friend leukemia integration 1 (FLI1) has such a decis...
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| Veröffentlicht in: | Blood |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4463808/ https://ncbi.nlm.nih.gov/pubmed/25911237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-610519 |
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