RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation

The activity of antagonizing transcription factors represents a mechanistic paradigm of bidirectional lineage–fate control during hematopoiesis. At the megakaryocytic/erythroid bifurcation, the crossantagonism of krueppel-like factor 1 (KLF1) and friend leukemia integration 1 (FLI1) has such a decis...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Kuvardina, Olga N., Herglotz, Julia, Kolodziej, Stephan, Kohrs, Nicole, Herkt, Stefanie, Wojcik, Bartosch, Oellerich, Thomas, Corso, Jasmin, Behrens, Kira, Kumar, Ashok, Hussong, Helge, Urlaub, Henning, Koch, Joachim, Serve, Hubert, Bonig, Halvard, Stocking, Carol, Rieger, Michael A., Lausen, Jörn
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463808/
https://ncbi.nlm.nih.gov/pubmed/25911237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-610519
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