RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation

The activity of antagonizing transcription factors represents a mechanistic paradigm of bidirectional lineage–fate control during hematopoiesis. At the megakaryocytic/erythroid bifurcation, the crossantagonism of krueppel-like factor 1 (KLF1) and friend leukemia integration 1 (FLI1) has such a decis...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood
Prif Awduron: Kuvardina, Olga N., Herglotz, Julia, Kolodziej, Stephan, Kohrs, Nicole, Herkt, Stefanie, Wojcik, Bartosch, Oellerich, Thomas, Corso, Jasmin, Behrens, Kira, Kumar, Ashok, Hussong, Helge, Urlaub, Henning, Koch, Joachim, Serve, Hubert, Bonig, Halvard, Stocking, Carol, Rieger, Michael A., Lausen, Jörn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2015
Pynciau:
Hematopoiesis and Stem Cells
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463808/
https://ncbi.nlm.nih.gov/pubmed/25911237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-610519
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