RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation

The activity of antagonizing transcription factors represents a mechanistic paradigm of bidirectional lineage–fate control during hematopoiesis. At the megakaryocytic/erythroid bifurcation, the crossantagonism of krueppel-like factor 1 (KLF1) and friend leukemia integration 1 (FLI1) has such a decis...

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Bibliografische gegevens
Gepubliceerd in:Blood
Hoofdauteurs: Kuvardina, Olga N., Herglotz, Julia, Kolodziej, Stephan, Kohrs, Nicole, Herkt, Stefanie, Wojcik, Bartosch, Oellerich, Thomas, Corso, Jasmin, Behrens, Kira, Kumar, Ashok, Hussong, Helge, Urlaub, Henning, Koch, Joachim, Serve, Hubert, Bonig, Halvard, Stocking, Carol, Rieger, Michael A., Lausen, Jörn
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2015
Onderwerpen:
Hematopoiesis and Stem Cells
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463808/
https://ncbi.nlm.nih.gov/pubmed/25911237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-610519
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