MiR144/451 Expression Is Repressed by RUNX1 During Megakaryopoiesis and Disturbed by RUNX1/ETO

A network of lineage-specific transcription factors and microRNAs tightly regulates differentiation of hematopoietic stem cells along the distinct lineages. Deregulation of this regulatory network contributes to impaired lineage fidelity and leukemogenesis. We found that the hematopoietic master reg...

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Vydáno v:PLoS Genet
Hlavní autoři: Kohrs, Nicole, Kolodziej, Stephan, Kuvardina, Olga N., Herglotz, Julia, Yillah, Jasmin, Herkt, Stefanie, Piechatzek, Alexander, Salinas Riester, Gabriela, Lingner, Thomas, Wichmann, Christian, Bonig, Halvard, Seifried, Erhard, Platzbecker, Uwe, Medyouf, Hind, Grez, Manuel, Lausen, Jörn
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798443/
https://ncbi.nlm.nih.gov/pubmed/26990877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005946
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