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CD8(+) T cell evasion mandates CD4(+) T cell control of chronic gamma-herpesvirus infection
Gamma-herpesvirus infections are regulated by both CD4(+) and CD8(+) T cells. However clinical disease occurs mainly in CD4(+) T cell-deficient hosts. In CD4(+) T cell-deficient mice, CD8(+) T cells control acute but not chronic lung infection by Murid Herpesvirus-4 (MuHV-4). We show that acute and...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5398720/ https://ncbi.nlm.nih.gov/pubmed/28394921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006311 |
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