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Type I Interferon Signaling to Dendritic Cells Limits Murid Herpesvirus 4 Spread from the Olfactory Epithelium

Murid herpesvirus 4 (MuHV-4) is a B cell-tropic gammaherpesvirus that can be studied in vivo. Despite viral evasion, type I interferons (IFN-I) limit its spread. After MuHV-4 inoculation into footpads, IFN-I protect lymph node subcapsular sinus macrophages (SSM) against productive infection; after p...

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Publicado en:J Virol
Autores principales: Lawler, Clara, Stevenson, Philip G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686760/
https://ncbi.nlm.nih.gov/pubmed/28904198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00951-17
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