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Glycoprotein B Cleavage Is Important for Murid Herpesvirus 4 To Infect Myeloid Cells

Glycoprotein B (gB) is a conserved herpesvirus virion component implicated in membrane fusion. As with many—but not all—herpesviruses, the gB of murid herpesvirus 4 (MuHV-4) is cleaved into disulfide-linked subunits, apparently by furin. Preventing gB cleavage for some herpesviruses causes minor inf...

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Auteurs principaux: Glauser, Daniel L., Milho, Ricardo, Frederico, Bruno, May, Janet S., Kratz, Anne-Sophie, Gillet, Laurent, Stevenson, Philip G.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807390/
https://ncbi.nlm.nih.gov/pubmed/23903840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00709-13
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