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Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells

A unique experimental model has been developed for dissecting the integrity of CD8+ T cell-mediated immunity to a persistent gammaherpesvirus under conditions of CD4+ T cell deficiency. Respiratory challenge of major histocompatibility complex class II -/- and +/+ C57BL/6J mice with the murine gamma...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192775/
https://ncbi.nlm.nih.gov/pubmed/9064346
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