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DNA damage induces expression of WWP1 to target ΔNp63α to degradation

ΔNp63αplays key roles in cell survival and proliferation. So its expression is always tightly controlled in cells. We previously reported that DNA damage down-regulates transcription of ΔNp63αin FaDu and HaCat cells, which contributes to cell apoptosis. In the present study, we found that DNA damage...

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Publicat a:PLoS One
Autors principals: Chen, Ji, Shi, Hua, Chen, Yonglong, Fan, Shijie, Liu, Dingyi, Li, Chenghua
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398614/
https://ncbi.nlm.nih.gov/pubmed/28426804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176142
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