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ATM kinase is a master switch for the ΔNp63α phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage
We previously found that the pro-apoptotic DNA damaging agent, cisplatin, mediated the proteasome-dependent degradation of ΔNp63α associated with its increased phosphorylated status. Since ΔNp63α usually plays an opposite role to p53 and TAp63 in human cancers, we tested the notion that phosphorylat...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069617/ https://ncbi.nlm.nih.gov/pubmed/18769144 |
| Etiketak: |
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