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ATM kinase is a master switch for the ΔNp63α phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage
We previously found that the pro-apoptotic DNA damaging agent, cisplatin, mediated the proteasome-dependent degradation of ΔNp63α associated with its increased phosphorylated status. Since ΔNp63α usually plays an opposite role to p53 and TAp63 in human cancers, we tested the notion that phosphorylat...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069617/ https://ncbi.nlm.nih.gov/pubmed/18769144 |
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