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Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells
Head and neck squamous cell carcinoma (HNSCC) cells exposed to cisplatin (CIS) displayed a dramatic ATM-dependent phosphorylation of ΔNp63α that leads to the transcriptional regulation of downstream mRNAs. Here, we report that phospho (p)-ΔNp63α transcriptionally deregulates miRNA expression after C...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131951/ https://ncbi.nlm.nih.gov/pubmed/21274007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.188 |
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