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Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure

The cisplatin-induced ATM-dependent phosphorylated (p)-ΔNp63α plays an important role in transcriptional regulation of specific genes encoding mRNAs and microRNAs (miRs) implicated in cell death, cell survival and chemoresistance. The p-ΔNp63α-induced miR-885-3p functions as a critical regulator of...

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Bibliographic Details
Main Authors: Huang, Yiping, Chuang, Alice Y, Ratovitski, Edward A
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266119/
https://ncbi.nlm.nih.gov/pubmed/22071691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.22.18107
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