Multiple components of PKA and TGF-β pathways are mutated in pseudomyxoma peritonei

Pseudomyxoma peritonei (PMP) is a subtype of mucinous adenocarcinoma mainly restricted to the peritoneal cavity and most commonly originating from the appendix. The genetic background of PMP is poorly understood and no targeted treatments are currently available for this fatal disease. While RAS sig...

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Veröffentlicht in:PLoS One
Hauptverfasser: Saarinen, Lilli, Nummela, Pirjo, Thiel, Alexandra, Lehtonen, Rainer, Järvinen, Petrus, Järvinen, Heikki, Aaltonen, Lauri A., Lepistö, Anna, Hautaniemi, Sampsa, Ristimäki, Ari
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398530/
https://ncbi.nlm.nih.gov/pubmed/28426742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174898
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