Multiple components of PKA and TGF-β pathways are mutated in pseudomyxoma peritonei

Pseudomyxoma peritonei (PMP) is a subtype of mucinous adenocarcinoma mainly restricted to the peritoneal cavity and most commonly originating from the appendix. The genetic background of PMP is poorly understood and no targeted treatments are currently available for this fatal disease. While RAS sig...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Saarinen, Lilli, Nummela, Pirjo, Thiel, Alexandra, Lehtonen, Rainer, Järvinen, Petrus, Järvinen, Heikki, Aaltonen, Lauri A., Lepistö, Anna, Hautaniemi, Sampsa, Ristimäki, Ari
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398530/
https://ncbi.nlm.nih.gov/pubmed/28426742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174898
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