Multiple components of PKA and TGF-β pathways are mutated in pseudomyxoma peritonei

Pseudomyxoma peritonei (PMP) is a subtype of mucinous adenocarcinoma mainly restricted to the peritoneal cavity and most commonly originating from the appendix. The genetic background of PMP is poorly understood and no targeted treatments are currently available for this fatal disease. While RAS sig...

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Publicado en:PLoS One
Autores principales: Saarinen, Lilli, Nummela, Pirjo, Thiel, Alexandra, Lehtonen, Rainer, Järvinen, Petrus, Järvinen, Heikki, Aaltonen, Lauri A., Lepistö, Anna, Hautaniemi, Sampsa, Ristimäki, Ari
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398530/
https://ncbi.nlm.nih.gov/pubmed/28426742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174898
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