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Multiple components of PKA and TGF-β pathways are mutated in pseudomyxoma peritonei

Pseudomyxoma peritonei (PMP) is a subtype of mucinous adenocarcinoma mainly restricted to the peritoneal cavity and most commonly originating from the appendix. The genetic background of PMP is poorly understood and no targeted treatments are currently available for this fatal disease. While RAS sig...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Saarinen, Lilli, Nummela, Pirjo, Thiel, Alexandra, Lehtonen, Rainer, Järvinen, Petrus, Järvinen, Heikki, Aaltonen, Lauri A., Lepistö, Anna, Hautaniemi, Sampsa, Ristimäki, Ari
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398530/
https://ncbi.nlm.nih.gov/pubmed/28426742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174898
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