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Human Bub1 protects centromeric sister-chromatid cohesion through Shugoshin during mitosis

Sister chromatids in mammalian cells remain attached mostly at their centromeres at metaphase because of the loss of cohesion along chromosome arms in prophase. Here, we report that Bub1 retains centromeric cohesion in mitosis of human cells. Depletion of Bub1 or Shugoshin (Sgo1) in HeLa cells by RN...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tang, Zhanyun, Sun, Yuxiao, Harley, Sara E., Zou, Hui, Yu, Hongtao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC539817/
https://ncbi.nlm.nih.gov/pubmed/15604152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408600102
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