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Human Bub1 protects centromeric sister-chromatid cohesion through Shugoshin during mitosis
Sister chromatids in mammalian cells remain attached mostly at their centromeres at metaphase because of the loss of cohesion along chromosome arms in prophase. Here, we report that Bub1 retains centromeric cohesion in mitosis of human cells. Depletion of Bub1 or Shugoshin (Sgo1) in HeLa cells by RN...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC539817/ https://ncbi.nlm.nih.gov/pubmed/15604152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408600102 |
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