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Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells

Human Shugoshin 1 (Sgo1) protects centromeric sister-chromatid cohesion during prophase and prevents premature sister-chromatid separation. Heterochromatin protein 1 (HP1) has been proposed to protect centromeric sister-chromatid cohesion by directly targeting Sgo1 to centromeres in mitosis. Here we...

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Detalhes bibliográficos
Main Authors: Kang, Jungseog, Chaudhary, Jaideep, Dong, Hui, Kim, Soonjoung, Brautigam, Chad A., Yu, Hongtao
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078076/
https://ncbi.nlm.nih.gov/pubmed/21346195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-01-0009
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