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Identification of a serpin-enzyme complex receptor on human hepatoma cells and human monocytes.

Formation of the covalently stabilized complex of alpha 1-antitrypsin (alpha 1-AT) with neutrophil elastase, the archetype of serine proteinase inhibitor serpin-enzyme complexes, is associated with structural rearrangement of the alpha 1-AT molecule and hydrolysis of a reactive-site peptide bond. An...

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Detalhes bibliográficos
Main Authors: Perlmutter, D H, Glover, G I, Rivetna, M, Schasteen, C S, Fallon, R J
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC53981/
https://ncbi.nlm.nih.gov/pubmed/2160076
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