Identification of calcium-activated neutral protease as a processing enzyme of human interleukin 1 alpha.

We describe here the involvement of calcium-activated neutral protease (CANP or calpain, EC 3.4.22.17) in calcium-dependent proteolytic processing of the precursor of human interleukin 1 alpha (IL-1 alpha) into mature IL-1 alpha. Calcium ionophore ionomycin enhanced proteolytic processing of pre-IL-...

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Detalhes bibliográficos
Main Authors: Kobayashi, Y, Yamamoto, K, Saido, T, Kawasaki, H, Oppenheim, J J, Matsushima, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC54362/
https://ncbi.nlm.nih.gov/pubmed/2115174
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