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Impact of population structure, effective bottleneck time, and allele frequency on linkage disequilibrium maps
Genetic maps in linkage disequilibrium (LD) units play the same role for association mapping as maps in centimorgans provide at much lower resolution for linkage mapping. Association mapping of genes determining disease susceptibility and other phenotypes is based on the theory of LD, here applied t...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC539799/ https://ncbi.nlm.nih.gov/pubmed/15604137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408251102 |
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