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Impact of population structure, effective bottleneck time, and allele frequency on linkage disequilibrium maps

Genetic maps in linkage disequilibrium (LD) units play the same role for association mapping as maps in centimorgans provide at much lower resolution for linkage mapping. Association mapping of genes determining disease susceptibility and other phenotypes is based on the theory of LD, here applied t...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Zhang, Weihua, Collins, Andrew, Gibson, Jane, Tapper, William J., Hunt, Sarah, Deloukas, Panos, Bentley, David R., Morton, Newton E.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC539799/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15604137/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408251102
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