Contribution of Secreted NADase and Streptolysin O to the Pathogenesis of Epidemic Serotype M1 Streptococcus pyogenes Infections

Streptococcus pyogenes secretes many toxins that facilitate human colonization, invasion, and dissemination. NADase (SPN) and streptolysin O (SLO) are two toxins that play important roles in pathogenesis. We previously showed that increased production of SPN and SLO in epidemic serotype M1 and M89 S...

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Veröffentlicht in:Am J Pathol
Hauptverfasser: Zhu, Luchang, Olsen, Randall J., Lee, Jessica D., Porter, Adeline R., DeLeo, Frank R., Musser, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2017
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Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397666/
https://ncbi.nlm.nih.gov/pubmed/28034602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.11.003
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