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Genetic heterogeneity of the Spy1336/R28—Spy1337 virulence axis in Streptococcus pyogenes and effect on gene transcript levels and pathogenesis

Streptococcus pyogenes is a strict human pathogen responsible for more than 700 million infections annually worldwide. Strains of serotype M28 S. pyogenes are typically among the five more abundant types causing invasive infections and pharyngitis in adults and children. Type M28 strains also have a...

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Veröffentlicht in:PLoS One
Hauptverfasser: Eraso, Jesus M., Kachroo, Priyanka, Olsen, Randall J., Beres, Stephen B., Zhu, Luchang, Badu, Traci, Shannon, Sydney, Cantu, Concepcion C., Saavedra, Matthew Ojeda, Kubiak, Samantha L., Porter, Adeline R., DeLeo, Frank R., Musser, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098570/
https://ncbi.nlm.nih.gov/pubmed/32214338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229064
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