TM6SF2 rs58542926 impacts lipid processing in liver and small intestine

The transmembrane 6 superfamily member 2 (TM6SF2) loss-of-function variant, rs58542926, is a genetic risk factor for nonalcoholic fatty liver disease and progression to fibrosis, but is paradoxically associated with lower levels of hepatic-derived triglyceride-rich lipoproteins (TRLs). TM6SF2 is exp...

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書誌詳細
出版年:Hepatology
主要な著者: O’Hare, Elizabeth A., Yang, Rongze, Yerges-Armstrong, Laura, Sreenivasan, Urmilla, McFarland, Rebecca, Leitch, Carmen C., Wilson, Meredith H., Narina, Shilpa, Gorden, Alexis, Ryan, Kathy, Shuldiner, Alan R., Farber, Steve A., Wood, G. Craig, Still, Christopher D., Gerhard, Glenn S., Robishaw, Janet D., Sztalryd, Carole, Zaghloul, Norann A.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397347/
https://ncbi.nlm.nih.gov/pubmed/28027591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29021
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