TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is an increasingly common condition, strongly associated with the metabolic syndrome, that can lead to progressive hepatic fibrosis, cirrhosis and hepatic failure. Subtle inter-patient genetic variation and environmental factors combine to determine variatio...

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Vydáno v:Nat Commun
Hlavní autoři: Liu, Yang-Lin, Reeves, Helen L., Burt, Alastair D., Tiniakos, Dina, McPherson, Stuart, Leathart, Julian B. S., Allison, Michael E. D., Alexander, Graeme J., Piguet, Anne-Christine, Anty, Rodolphe, Donaldson, Peter, Aithal, Guruprasad P., Francque, Sven, Van Gaal, Luc, Clement, Karine, Ratziu, Vlad, Dufour, Jean-Francois, Day, Christopher P., Daly, Ann K., Anstee, Quentin M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279183/
https://ncbi.nlm.nih.gov/pubmed/24978903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5309
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