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Bacterial subversion of cAMP signalling inhibits cathelicidin expression, which is required for innate resistance to Mycobacterium tuberculosis

Antimicrobial peptides such as cathelicidins are an important component of innate immune defence against inhaled microorganisms and have demonstrated antimicrobial activity against Mycobacterium tuberculosis with in vitro models. Despite this, little is known about the regulation and expression of c...

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Bibliografiske detaljer
Udgivet i:J Pathol
Main Authors: Gupta, Shashank, Winglee, Kathryn, Gallo, Richard, Bishai, William R
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397332/
https://ncbi.nlm.nih.gov/pubmed/28097645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4878
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