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Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice
Aging diminishes bone formation engendered by mechanical loads, but the mechanism for this impairment remains unclear. Because Wnt signaling is required for optimal loading-induced bone formation, we hypothesized that aging impairs the load-induced activation of Wnt signaling. We analyzed dynamic hi...
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| Publicado no: | J Bone Miner Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5397287/ https://ncbi.nlm.nih.gov/pubmed/27357062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2900 |
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