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The aging mouse partially models the aging human spine: lumbar and coccygeal disc height, composition, mechanical properties, and Wnt signaling in young and old mice

Murine lumbar and coccygeal (tail) regions of spines are commonly used to study cellular signaling of age-related disc diseases, but the tissue-level changes of aging intervertebral discs and vertebrae of each spinal region remain unclear. Furthermore, the impact of aging lumbar and coccygeal discs...

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Detalhes bibliográficos
Main Authors: Holguin, Nilsson, Aguilar, Rhiannon, Harland, Robin A., Bomar, Bradley A., Silva, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064379/
https://ncbi.nlm.nih.gov/pubmed/24790018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01322.2013
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