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The aging mouse partially models the aging human spine: lumbar and coccygeal disc height, composition, mechanical properties, and Wnt signaling in young and old mice

Murine lumbar and coccygeal (tail) regions of spines are commonly used to study cellular signaling of age-related disc diseases, but the tissue-level changes of aging intervertebral discs and vertebrae of each spinal region remain unclear. Furthermore, the impact of aging lumbar and coccygeal discs...

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Hlavní autoři: Holguin, Nilsson, Aguilar, Rhiannon, Harland, Robin A., Bomar, Bradley A., Silva, Matthew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064379/
https://ncbi.nlm.nih.gov/pubmed/24790018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01322.2013
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