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Old Mice Have Less Transcriptional Activation But Similar Periosteal Cell Proliferation Compared to Young-Adult Mice in Response to in vivo Mechanical Loading

Mechanical loading is a potent strategy to induce bone formation, but with aging, the bone formation response to the same mechanical stimulus diminishes. Our main objectives were to (i) discover the potential transcriptional differences and (ii) compare the periosteal cell proliferation between tibi...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Chermside-Scabbo, Christopher J, Harris, Taylor L, Brodt, Michael D, Braenne, Ingrid, Zhang, Bo, Farber, Charles R, Silva, Matthew J
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486279/
https://ncbi.nlm.nih.gov/pubmed/32311160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.4031
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