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Regulation of Prp43-mediated disassembly of spliceosomes by its cofactors Ntr1 and Ntr2
The DEAH-box NTPase Prp43 disassembles spliceosomes in co-operation with the cofactors Ntr1/Spp382 and Ntr2, forming the NTR complex. How Prp43 is regulated by its cofactors to discard selectively only intron-lariat spliceosomes (ILS) and defective spliceosomes and to prevent disassembly of earlier...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5397206/ https://ncbi.nlm.nih.gov/pubmed/27923990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1225 |
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