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Chromosomal dynamics predicted by an elastic network model explains genome-wide accessibility and long-range couplings

Understanding the three-dimensional (3D) architecture of chromatin and its relation to gene expression and regulation is fundamental to understanding how the genome functions. Advances in Hi-C technology now permit us to study 3D genome organization, but we still lack an understanding of the structu...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Sauerwald, Natalie, Zhang, She, Kingsford, Carl, Bahar, Ivet
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397156/
https://ncbi.nlm.nih.gov/pubmed/28334818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx172
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