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Cimetidine synergizes with Praziquantel to enhance the immune response of HBV DNA vaccine via activating cytotoxic CD8(+) T cell

Previously, we have reported that either CIM or PZQ, 2 clinical drugs, could be used to develop as adjuvants on HBV DNA vaccine to elicit both humoral and cellular immune responses. Here, we demonstrate that combinations of CIM and PZQ as adjuvants for a HBV DNA vaccine, could induce much stronger a...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Xie, Xiaoping, Geng, Shuang, Liu, Hu, Li, Chaofan, Yang, Yuqin, Wang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396244/
https://ncbi.nlm.nih.gov/pubmed/24643207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.28517
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