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CD4(+) T cell-released exosomes inhibit CD8(+) cytotoxic T-lymphocyte responses and antitumor immunity

T cells secrete bioactive exosomes (EXO), but the potential immunoregulatory effect of T-cell EXO is largely unknown. In this study, we generated activated ovalbumin (OVA)-specific CD4(+) T cells in vitro via coculture of OVA-pulsed dendritic cells (DC(OVA)) with naive CD4(+) T cells derived from OV...

詳細記述

保存先:
書誌詳細
主要な著者: Zhang, Haifeng, Xie, Yufeng, Li, Wei, Chibbar, Rajni, Xiong, Sidong, Xiang, Jim
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002994/
https://ncbi.nlm.nih.gov/pubmed/21200381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2010.59
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