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Cimetidine synergizes with Praziquantel to enhance the immune response of HBV DNA vaccine via activating cytotoxic CD8(+) T cell

Previously, we have reported that either CIM or PZQ, 2 clinical drugs, could be used to develop as adjuvants on HBV DNA vaccine to elicit both humoral and cellular immune responses. Here, we demonstrate that combinations of CIM and PZQ as adjuvants for a HBV DNA vaccine, could induce much stronger a...

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Podrobná bibliografie
Vydáno v:Hum Vaccin Immunother
Hlavní autoři: Xie, Xiaoping, Geng, Shuang, Liu, Hu, Li, Chaofan, Yang, Yuqin, Wang, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396244/
https://ncbi.nlm.nih.gov/pubmed/24643207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.28517
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