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Autophagy promotes Braf (V600E)-driven lung tumorigenesis by preserving mitochondrial metabolism
The role of autophagy in cancer is complex and context-dependent. Here we describe work with genetically engineered mouse models of non-small cell lung cancer (NSCLC) in which the tumor-suppressive and tumor-promoting function of autophagy can be visualized in the same system. We discovered that ear...
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| Опубликовано в: : | Autophagy |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5396093/ https://ncbi.nlm.nih.gov/pubmed/24362353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27320 |
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