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Autophagy promotes Braf (V600E)-driven lung tumorigenesis by preserving mitochondrial metabolism

The role of autophagy in cancer is complex and context-dependent. Here we describe work with genetically engineered mouse models of non-small cell lung cancer (NSCLC) in which the tumor-suppressive and tumor-promoting function of autophagy can be visualized in the same system. We discovered that ear...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Strohecker, Anne M, White, Eileen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396093/
https://ncbi.nlm.nih.gov/pubmed/24362353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27320
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