The within-host population dynamics of Mycobacterium tuberculosis vary with treatment efficacy

BACKGROUND: Combination therapy is one of the most effective tools for limiting the emergence of drug resistance in pathogens. Despite the widespread adoption of combination therapy across diseases, drug resistance rates continue to rise, leading to failing treatment regimens. The mechanisms underly...

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發表在:Genome Biol
Main Authors: Trauner, Andrej, Liu, Qingyun, Via, Laura E., Liu, Xin, Ruan, Xianglin, Liang, Lili, Shi, Huimin, Chen, Ying, Wang, Ziling, Liang, Ruixia, Zhang, Wei, Wei, Wang, Gao, Jingcai, Sun, Gang, Brites, Daniela, England, Kathleen, Zhang, Guolong, Gagneux, Sebastien, Barry, Clifton E., Gao, Qian
格式: Artigo
語言:Inglês
出版: BioMed Central 2017
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395877/
https://ncbi.nlm.nih.gov/pubmed/28424085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1196-0
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